Emotional Leper wrote:
Yah. I got interested in Psychiatry due to my own mental problems. Bipolar II Disorder with Psychotic Features.
I've always been very interested in Bipolar Disorder -- my aunt has BP I, and she was diagnosed when I was about 5. She bought a gun and ran off to Arizona, and when my grandparents went to her house to look for her, they discovered
hundreds of things that she'd borrowed from various people (over about a 10 year period) -- a lot of those items were stupid little things like lotions and fingernail polish. She had put little sticky labels on each item, designating the people to whom they belonged, and laid them out (in alphabetical order) all over her living room.
Emotional Leper wrote:Spent years on SSRIs, which did nothing. My doctor figured out why a few months ago, after I'd been living (reasonably sanely) off the drugs for a few years, and found out that 5-HTP makes me manic as soon as it hits my system
From everything I've ever heard, anti-depressants are often the worst things for Bipolar people to take (because they're so likely to induce manic episodes), unless they're taken in conjunction with mood stabilizers. My aunt figured that out the hard way.
Emotional Leper wrote:and that Ecstacy has no effect on me beyond the methamphetamine effects. My brain's serotonin production capabilities seem to have been nearly completely destroyed. So, instead of Dopamine, Serotonin, and Norepinephrine, I just use Dopamine and Serotonin.
Ecstasy is a very tempermental drug, anyway, so I can see how a seratonin deficiency would render it (almost) inert. Interestingly, Ecstasy also fails to work for a lot of people who are taking mood stabilizers. I know this from various personal experiences, so I have no research to back it up. But it seems fairly intuitive, anyway -- medication (like Lithium) that affects/regulates norepinephrine and serotonin release and synthesis (respectively) would obviously have an impact on a drug like Ecstasy. The mitigating effect mood stabilizers sometimes have on Ecstasy seems to be greater than that of any (or almost any) other drug. One question, however, is whether the mood stabilizers themselves are the primary mitigating/preventative agent, or whether the individual's doubt/concern that the drug won't work prevents the expected drug response: sort of a "backward" placebo effect. I've had quite a few friends "psych themselves out" of their roll (which is a huge waste of money, might I add). I think it's probably a combination of the mood stabilizers and the mental state of the individual. Of course, mental state influences any drug, but Ecstasy is the only one I know of that can just
not work at all, based on your mindset.
Emotional Leper wrote:
we're talking about physical leprosy. Emotionally, I've already lost all feeling.

...Well, Linden has a "fixing things" complex of her own, so that might well be enough to win her over.